Transcriptomics

Dataset Information

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Cycle versus Pregnancy


ABSTRACT: At implantation the endometrium undergoes dramatic modifications necessary for its physical interactions with the trophoblast as well as the development of the conceptus. We aim to identify endometrial factors and pathways essential for a successful implantation in the caruncular [C] and the intercaruncular [IC] areas in cattle. Using a bovine oligo-array, expression profiles were established at day 20 of the estrous cycle or pregnancy (implantation) showing 446 and 1295 differentially expressed genes (DEG) in [C] and [IC] areas respectively. The impact of the conceptus was higher on the immune response function in [C] but more prominent on the regulation of metabolism function in [IC]. Keywords: Fluorescence Microarray 18 intercaruncular samples, 18 caruncular Samples. Comparisons of cycle (d20) and pregnancy (d20).

ORGANISM(S): Bos taurus  

SUBMITTER: Séverine Degrelle   XCindy Tian  Robin E Everts  Corinne Giraud-Delville  Laurent Galio  Julie Aubert  Pierrette Reinaud  Harris A Lewin  Isabelle Hue  Géraldine Taghouti  Nadéra Mansouri-Attia  Christophe Richard  Olivier Sandra  Jean-Paul Renard 

PROVIDER: E-GEOD-13664 | ArrayExpress | 2010-06-24

SECONDARY ACCESSION(S): GSE13664PRJNA110455

REPOSITORIES: GEO, ArrayExpress

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At implantation the endometrium undergoes modifications necessary for its physical interactions with the trophoblast as well as the development of the conceptus. We aim to identify endometrial factors and pathways essential for a successful implantation in the caruncular (C) and the intercaruncular (IC) areas in cattle. Using a 13,257-element bovine oligonucleotide array, we established expression profiles at day 20 of the estrous cycle or pregnancy (implantation), revealing 446 and 1,295 differ  ...[more]

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