Transcriptomics

Dataset Information

10

Comparative genomic hybridization of human breast cancer cell lines (45) on Affymetrix 100K SNP arrays


ABSTRACT: Breast cancer cell lines grown in full serum under standard conditions were profiled on Affymetrix GeneChip Mapping 100K Set Arrays Experiment Overall Design: Profiling of cell lines grown under standard conditions

ORGANISM(S): Homo sapiens  

SUBMITTER: Peter Haverty  

PROVIDER: E-GEOD-13696 | ArrayExpress | 2009-05-01

SECONDARY ACCESSION(S): GSE13696PRJNA110451

REPOSITORIES: GEO, ArrayExpress

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Publications


Breast cancers can be divided into subtypes with important implications for prognosis and treatment. We set out to characterize the genetic alterations observed in different breast cancer subtypes and to identify specific candidate genes and pathways associated with subtype biology. mRNA expression levels of estrogen receptor, progesterone receptor, and HER2 were shown to predict marker status determined by immunohistochemistry and to be effective at assigning samples to subtypes. HER2(+) cancer  ...[more]

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