Transcriptomics

Dataset Information

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Transcriptional profile of Candida parapsilosis in SD media


ABSTRACT: Partial genome microarray and plankton cells RNA was isolated from biofilms and from planktonic cells grown in SD media. Samples were labeled with either Cy5 or Cy3. Four independent biological replicates were compared, including dye swaps.

ORGANISM(S): Candida parapsilosis  

SUBMITTER: Tristan Rossignol  Geraldine Butler     

PROVIDER: E-GEOD-13717 | ArrayExpress | 2010-05-06

SECONDARY ACCESSION(S): GSE13717PRJNA114643

REPOSITORIES: GEO, ArrayExpress

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Publications

Correlation between biofilm formation and the hypoxic response in Candida parapsilosis.

Rossignol Tristan T   Ding Chen C   Guida Alessandro A   d'Enfert Christophe C   Higgins Desmond G DG   Butler Geraldine G  

Eukaryotic cell 20090116 4


The ability of Candida parapsilosis to form biofilms on indwelling medical devices is correlated with virulence. To identify genes that are important for biofilm formation, we used arrays representing approximately 4,000 open reading frames (ORFs) to compare the transcriptional profile of biofilm cells growing in a microfermentor under continuous flow conditions with that of cells in planktonic culture. The expression of genes involved in fatty acid and ergosterol metabolism and in glycolysis, i  ...[more]

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