Transcriptomics

Dataset Information

3

Profiling of adipose tissue from the F2 M16xICR mouse cross.


ABSTRACT: We profiled gene expression in adipose tissue from F2 progeny from a cross between the outbred M16 (selectively bred for rapid weight gain) and ICR (control) mouse strains. We developed a framework for reconstructing tissue-to-tissue coexpression networks between genes in hypothalamus, adipose or adipose tissues that are independent of networks constructed from single tissue analyses. The subnetworks we identify as specific to tissue-to-tissue interactions associate with multiple obesity-relevant biological functions like circadian rhythm, energy balance, stress response, or immune response. Keywords: Tissue profiling in a mouse F2 cross. We analyzed 308 adipose samples.

ORGANISM(S): Mus musculus  

SUBMITTER: Mark F Allan   Eric E Schadt  Daniel Pomp  Carmen Argman  Radu Dobrin  Jun Zhu  Mark E Parrish  Cliona Molony  Sonia Carlson 

PROVIDER: E-GEOD-13746 | ArrayExpress | 2009-10-25

SECONDARY ACCESSION(S): GSE13746PRJNA109399

REPOSITORIES: GEO, ArrayExpress

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