Transcriptomics

Dataset Information

5

Transcription profiling of normal adult rat extraocular muscle, cardiac muscle, leg (gastrocnemius-soleus) muscle and smooth muscle (stomach wall)


ABSTRACT: Comparison of normal adult rat extraocular muscle, cardiac muscle, leg (gastrocnemius-soleus) muscle and smooth muscle (stomach wall). Affymetrix microarray chip RG-U34A was used. MAS version 5 was used to analyze the muscle group differences. Data form part of publication: FASEB Journal 17: 1370-1372, 2003 (full length article available at http://www.fasebj.org/cgi/doi/10.1096/fj.02-1108fje).

INSTRUMENT(S): 418 [Affymetrix]

ORGANISM(S): Rattus norvegicus  

TISSUE(S): Stomach Wall Smooth Muscle, Extraocular Muscle, Gastrocnemius And Soleus Muscle, Cardiac Ventricle Muscle

SUBMITTER: Sangeeta Khanna  

PROVIDER: E-GEOD-142 | ArrayExpress | 2007-10-27

SECONDARY ACCESSION(S): GDS276GSE142PRJNA84535

REPOSITORIES: GEO, ArrayExpress

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Publications

Comprehensive expression profiling by muscle tissue class and identification of the molecular niche of extraocular muscle.

Khanna Sangeeta S   Merriam Anita P AP   Gong Bendi B   Leahy Patrick P   Porter John D JD  

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030701 10


Muscle tissue is an elegant model for biologic integration of structure with function and is frequently affected by a variety of inherited diseases. Traditional muscle classes--skeletal, cardiac, and smooth--share basic aspects of contractile and energetics mechanisms but also have distinctive role-specific adaptations. We used large-scale oligonucleotide microarrays to broaden knowledge of the adaptive expression patterns underlying muscle tissue differences and to identify transcript subsets t  ...[more]

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