Ontology highlight
ABSTRACT:
REANALYSED by: E-GEOD-14278
INSTRUMENT(S): 418 [Affymetrix]
ORGANISM(S): Homo sapiens
SUBMITTER: Paul McLaren
PROVIDER: E-GEOD-14278 | ArrayExpress | 2009-01-17
SECONDARY ACCESSION(S): GSE14278PRJNA114563
REPOSITORIES: GEO, ArrayExpress
McLaren Paul J PJ Ball T Blake TB Wachihi Charles C Jaoko Walter W Kelvin David J DJ Danesh Ali A Kimani Joshua J Plummer Francis A FA Fowke Keith R KR
The Journal of infectious diseases 20101101
Studies of human immunodeficiency virus (HIV)-exposed seronegative individuals are crucial to inform vaccine design. In the present study we demonstrated that HIV-exposed seronegative commercial sex workers produce lower levels of proinflammatory cytokines at baseline than HIV-negative control subjects. We also showed that CD4+ T cells of HIV-exposed seronegative commercial sex workers have a characteristically lower level of gene expression that can be seen in differentially expressed genes and ...[more]