Transcriptomics

Dataset Information

0

Transcription profiling of human Treg and Th clones - experiment I


ABSTRACT: The aim of this work was to identify functional features that are specific of human Treg cells, through the identification of genes that are differentially expressed: 1/ in activated Treg clones versus activated Thelper clones; 2/ in Th clones activated in the presence versus the absence of TGFb; 3/ in suppressed Th clones, i.e. Th clones activated in the presence of Treg clones, versus controls. Experiment Overall Design: Two to four million cells of human T cell clones were collected at rest (time point = 0) or after activation with coated anti-CD3 and soluble anti-CD28 antibodies (time points = 6, 24 or 41hrs). RNA was extracted for hybridization on Affymetrix microarrays.

INSTRUMENT(S): 418 [Affymetrix]

ORGANISM(S): Homo sapiens  

SUBMITTER: Sophie Lucas   

PROVIDER: E-GEOD-14330 | ArrayExpress | 2009-01-17

SECONDARY ACCESSION(S): GSE14330PRJNA111445

REPOSITORIES: GEO, ArrayExpress

altmetric image

Publications

Sorry, this publication's infomation has not been loaded in the Indexer, please go directly to PUBMED or Altmetric.

Similar Datasets

2013-06-06 | E-GEOD-47636 | ArrayExpress
2009-09-15 | E-GEOD-16210 | ArrayExpress
2013-05-31 | E-GEOD-47510 | ArrayExpress
2016-04-06 | E-GEOD-70620 | ArrayExpress
2012-01-18 | E-GEOD-28130 | ArrayExpress
2009-01-09 | GSE14330 | GEO
2013-09-11 | E-GEOD-50729 | ArrayExpress
2016-04-06 | E-GEOD-70708 | ArrayExpress
2015-05-06 | E-GEOD-65650 | ArrayExpress
2013-08-31 | E-GEOD-49380 | ArrayExpress