Transcriptomics,Multiomics

Dataset Information

2

Transcription profiling of rat aortic and endocardial endothelial cells


ABSTRACT: Endocardial (EE) and Aortic (AE) endothelial cells were isolated from the same two rats, pooled (EE and AE kept separately) and cultured for 2 passages. Culture conditions and confluence of EE and AE cell cultures were kept as identical as possible. RNA was isolated and the expression profile of both endothelial cell types was compared using the Affymetrix rat genome U34A array.

OTHER RELATED OMICS DATASETS IN: PRJNA90069

INSTRUMENT(S): 418 [Affymetrix]

ORGANISM(S): Rattus norvegicus  

SUBMITTER: Jan Hendrickx  

PROVIDER: E-GEOD-1478 | ArrayExpress | 2008-06-11

SECONDARY ACCESSION(S): GDS695GSE1478PRJNA90069

REPOSITORIES: GEO, ArrayExpress

Dataset's files

Source:
Action DRS
E-GEOD-1478.README.txt Txt
E-GEOD-1478.eSet.r Other
E-GEOD-1478.idf.txt Idf
E-GEOD-1478.processed.1.zip Processed
E-GEOD-1478.raw.1.zip Raw
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Publications

Molecular diversity of cardiac endothelial cells in vitro and in vivo.

Hendrickx Jan J   Doggen Kris K   Weinberg Ellen O EO   Van Tongelen Pascale P   Fransen Paul P   De Keulenaer Gilles W GW  

Physiological genomics 20040810 2


In addition to a number of common features, cardiovascular endothelium displays structural, functional, and genetic differences according to its position in the cardiovascular tree. In the heart, endocardial and cardiac microvascular endothelia (CMVE) interact directly with surrounding cardiomyocytes, whereas the endothelium within blood vessels interacts with smooth muscle cells. In this study, we investigated whether cardiac endothelial cells were distinct from aortic endothelial (AE) cells at  ...[more]

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