Transcriptomics

Dataset Information

651

Genomic comparisons of Salmonella enterica serovar Paratyphi A isolates


ABSTRACT: Comparative genomic analysis of a temporally and locally diverse set of S. enterica ssp I sv Paratyphi A isolates Keywords: ordered

ORGANISM(S): Salmonella enterica subsp. enterica serovar Paratyphi A  

SUBMITTER: Jerry Reen   Carmen Choy  Steffen Porwollik  Pui Cheng  Michael McClelland 

PROVIDER: E-GEOD-1500 | ArrayExpress | 2004-07-21

SECONDARY ACCESSION(S): GSE1500PRJNA90825

REPOSITORIES: GEO, ArrayExpress

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Publications

Comparison of genome degradation in Paratyphi A and Typhi, human-restricted serovars of Salmonella enterica that cause typhoid.

McClelland Michael M   Sanderson Kenneth E KE   Clifton Sandra W SW   Latreille Phil P   Porwollik Steffen S   Sabo Aniko A   Meyer Rekha R   Bieri Tamberlyn T   Ozersky Phil P   McLellan Michael M   Harkins C Richard CR   Wang Chunyan C   Nguyen Christine C   Berghoff Amy A   Elliott Glendoria G   Kohlberg Sara S   Strong Cindy C   Du Feiyu F   Carter Jason J   Kremizki Colin C   Layman Dan D   Leonard Shawn S   Sun Hui H   Fulton Lucinda L   Nash William W   Miner Tracie T   Minx Patrick P   Delehaunty Kim K   Fronick Catrina C   Magrini Vincent V   Nhan Michael M   Warren Wesley W   Florea Liliana L   Spieth John J   Wilson Richard K RK  

Nature genetics 20041107 12


Salmonella enterica serovars often have a broad host range, and some cause both gastrointestinal and systemic disease. But the serovars Paratyphi A and Typhi are restricted to humans and cause only systemic disease. It has been estimated that Typhi arose in the last few thousand years. The sequence and microarray analysis of the Paratyphi A genome indicates that it is similar to the Typhi genome but suggests that it has a more recent evolutionary origin. Both genomes have independently accumulat  ...[more]

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