Transcriptomics

Dataset Information

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RNAi profiling of human Kasumi-1 AML1-ETO knockdown samples


ABSTRACT: Kasumi-1 AML cells that were transfected in triplicate with AML1-ETO or luciferase siRNA constructs by either Amaxa nucleofection or Biorad siLentFect and incubated for 96 hours. Microarrays used to discover an AML1-ETO signature for a GE-HTS screen to identify AML1-ETO modulators. Experiment Overall Design: Kasumi-1 AML cells incubated for 96 hours after they were transfected in triplicate with AML1-ETO or luciferase siRNA constructs by either Amaxa nucleofection or Biorad siLentFect along with three control samples not transfected with a construct.

INSTRUMENT(S): 418 [Affymetrix]

ORGANISM(S): Homo sapiens  

SUBMITTER: Kimberly Stegmaier  

PROVIDER: E-GEOD-15646 | ArrayExpress | 2009-05-11

SECONDARY ACCESSION(S): GSE15646PRJNA122929

REPOSITORIES: GEO, ArrayExpress

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