Transcriptomics,Multiomics

Dataset Information

48

Gene expression of side population and main population cells, isolated from adult murine skeletal muscle and bone marrow


ABSTRACT: This study identified gene expression of Side Population (SP) and Main Population (MP) cells, isolated from adult murine skeletal muscle and Bone Marrow. Five different preparations of muscle SP, muscle MP, Bone marrw SP and Bone marrow MP cells were used as replicates. SUBMITTER_CITATION: Liadaki K, Kho AT, Sanoudou D, Schienda J, Flint A, Beggs AH, Kohane IS, Kunkel LM. Side population cells isolated from different tissues share transcriptome signatures and express tissue-specific markers. Exp Cell Res. 2005;303(2):360-74.

REANALYSED by: E-GEOD-1571

INSTRUMENT(S): 418 [Affymetrix]

ORGANISM(S): Mus musculus  

SUBMITTER: Kalliopi Liadaki   

PROVIDER: E-GEOD-1571 | ArrayExpress | 2015-09-02

SECONDARY ACCESSION(S): GSE1571GDS1010PRJNA90807

REPOSITORIES: GEO, ArrayExpress

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Publications

Side population cells isolated from different tissues share transcriptome signatures and express tissue-specific markers.

Liadaki K K   Kho A T AT   Sanoudou D D   Schienda J J   Flint A A   Beggs A H AH   Kohane I S IS   Kunkel L M LM  

Experimental cell research 20041111 2


Side Population (SP) cells, isolated from murine adult bone marrow (BM) based on the exclusion of the DNA dye Hoechst 33342, exhibit potent hematopoietic stem cell (HSC) activity when compared to Main Population (MP) cells. Furthermore, SP cells derived from murine skeletal muscle exhibit both hematopoietic and myogenic potential in vivo. The multipotential capacity of SP cells isolated from variable tissues is supported by an increasing number of studies. To investigate whether the SP phenotype  ...[more]

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