Transcriptomics

Dataset Information

3

Transcription profiling of human blood from healthy individuals, a longitudinal study


ABSTRACT: The gene expression profile of blood drawn from healthy individuals was studied over a period of six months, at five time points. The gene expression profiles appeared to be constant over one month and to slightly vary over three months. A small proportion of genes were found to be differentially regulated according to gender. Differential gene regulation by age (in subjects 25â??55 years of age versus subjects > 55 years of age) was not observed. Experiment Overall Design: Healthy subjects were enrolled at a single site, their health status was determined by medical history, physical examination, and standard laboratory test values. Venous blood was drawn in the morning, from fasted subjects at five time points (Day1, Day14, Day28, Day 90 and Day 180). Blood was collected into PAXgene tubes (Becton-Dickinson Diagnostics; Hombrechtikon, Switzerland).

INSTRUMENT(S): 418 [Affymetrix]

ORGANISM(S): Homo sapiens  

SUBMITTER: Guillemette Duchateau-Nguyen  

PROVIDER: E-GEOD-16028 | ArrayExpress | 2009-05-17

SECONDARY ACCESSION(S): GSE16028PRJNA115381

REPOSITORIES: GEO, ArrayExpress

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