Transcriptomics

Dataset Information

4

Transcription profiling of human human neuroblastoma SH-SY5Y cells identifies molecular effectors of unconjugated bilirubin


ABSTRACT: This SuperSeries is composed of the following subset Series:; GSE16656: Transcriptome analysis identifies molecular effectors of unconjugated bilirubin in human neuroblatoma SH-SY5Y cells: 24h; GSE16766: Transcriptome analysis identifies molecular effectors of unconjugated bilirubin in human neuroblastoma SH-SY5Y cells: 1h; GSE16767: Transcriptome analysis identifies molecular effectors of unconjugated bilirubin in human neuroblastoma SH-SY5Y cells: 4h Experiment Overall Design: Refer to individual Series

INSTRUMENT(S): 418 [Affymetrix]

ORGANISM(S): Homo sapiens  

SUBMITTER: Paola Roncaglia 

PROVIDER: E-GEOD-16768 | ArrayExpress | 2009-12-02

SECONDARY ACCESSION(S): GSE16768PRJNA117525

REPOSITORIES: GEO, ArrayExpress

altmetric image

Publications

A transcriptome analysis identifies molecular effectors of unconjugated bilirubin in human neuroblastoma SH-SY5Y cells.

Calligaris Raffaella R   Bellarosa Cristina C   Foti Rossana R   Roncaglia Paola P   Giraudi Pablo P   Krmac Helena H   Tiribelli Claudio C   Gustincich Stefano S  

BMC genomics 20091119


<h4>Background</h4>The deposition of unconjugated bilirubin (UCB) in selected regions of the brain results in irreversible neuronal damage, or Bilirubin Encephalopathy (BE). Although UCB impairs a large number of cellular functions in other tissues, the basic mechanisms of neurotoxicity have not yet been fully clarified. While cells can accumulate UCB by passive diffusion, cell protection may involve multiple mechanisms including the extrusion of the pigment as well as pro-survival homeostatic r  ...[more]

Similar Datasets

2009-11-29 | E-GEOD-16766 | ArrayExpress
2009-12-02 | E-GEOD-16767 | ArrayExpress
2009-11-29 | E-GEOD-16656 | ArrayExpress
| PRJNA117525 | ENA
| PRJNA122739 | ENA
| PRJNA122727 | ENA
| PRJNA122787 | ENA
2009-11-19 | GSE16656 | GEO
2009-11-19 | GSE16767 | GEO
2009-11-19 | GSE16766 | GEO