Transcriptomics,Multiomics

Dataset Information

6

Transcription signature of Multiple Sclerosis


ABSTRACT: This SuperSeries is composed of the following subset Series: GSE17393: Transcription signature of Multiple Sclerosis in peripheral blood mononuclear cells. GSE17409: Pregnancy changes expression in peripheral blood mononuclear cells of healthy donors GSE17410: Pregnancy changes expression in peripheral blood mononuclear cells of Multiple Sclerosis (MS) patients Refer to individual Series

OTHER RELATED OMICS DATASETS IN: PRJNA123615PRJNA118877PRJNA123613PRJNA123611

ORGANISM(S): Homo Sapiens

SUBMITTER: Raffaele A Calogero  

PROVIDER: E-GEOD-17449 | ArrayExpress | 2010-01-10

SECONDARY ACCESSION(S): GSE17449PRJNA118877

REPOSITORIES: GEO, ArrayExpress

Dataset's files

Source:
Action DRS
E-GEOD-17449.README.txt Txt
E-GEOD-17449.eSet.r Other
E-GEOD-17449.idf.txt Idf
E-GEOD-17449.processed.1.zip Processed
E-GEOD-17449.raw.1.zip Raw
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Publications

Learning from nature: pregnancy changes the expression of inflammation-related genes in patients with multiple sclerosis.

Gilli Francesca F   Lindberg Raija L P RL   Valentino Paola P   Marnetto Fabiana F   Malucchi Simona S   Sala Arianna A   Capobianco Marco M   di Sapio Alessia A   Sperli Francesca F   Kappos Ludwig L   Calogero Raffaele A RA   Bertolotto Antonio A  

PloS one 20100129 1


<h4>Background</h4>Pregnancy is associated with reduced activity of multiple sclerosis (MS). However, the biological mechanisms underlying this pregnancy-related decrease in disease activity are poorly understood.<h4>Methodology</h4>We conducted a genome-wide transcription analysis in peripheral blood mononuclear cells (PBMCs) from 12 women (7 MS patients and 5 healthy controls) followed during their pregnancy. Samples were obtained before, during (i.e. at the third, sixth, and ninth month of ge  ...[more]

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