Ontology highlight
ABSTRACT:
OTHER RELATED OMICS DATASETS IN: PRJNA120037
ORGANISM(S): Rattus norvegicus
SUBMITTER: Amy N Fullenkamp Neville C Tam Shuk-Mei Ho Johannes M Freudenberg Mario Medvedovic Carol Y Szeto
PROVIDER: E-GEOD-17819 | ArrayExpress | 2010-05-09
SECONDARY ACCESSION(S): GSE17819PRJNA120037
REPOSITORIES: GEO, ArrayExpress
Action | DRS | |||
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E-GEOD-17819.README.txt | Txt | |||
E-GEOD-17819.eSet.r | Other | |||
E-GEOD-17819.idf.txt | Idf | |||
E-GEOD-17819.processed.1.zip | Processed | |||
E-GEOD-17819.raw.1.zip | Raw |
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Tam Neville N C NN Szeto Carol Y Y CY Freudenberg Johannes M JM Fullenkamp Amy N AN Medvedovic Mario M Ho Shuk-Mei SM
Molecular endocrinology (Baltimore, Md.) 20100922 11
Cotreatment with testosterone (T) and 17β-estradiol (E2) is an established regimen for inducing of prostatic intraepithelial neoplasia (PIN) and prostate cancer in rodent models. We previously used the pure antiestrogen ICI 182,780 (ICI) and bromocriptine, a dopamine receptor agonist, to inhibit PIN induction and systemic hyperprolactinemia in Noble rats and found that the carcinogenic action of T+E2 is mediated directly by the effects of E2 on the prostate and/or indirectly via E2-induced hyper ...[more]