Transcriptomics,Multiomics

Dataset Information

4

Drosophila 16-20 hrs embryos: DHR3G60S/Df(2R)12 vs. w1118


ABSTRACT: Transcriptional profiling of 16-20 hrs Drosophila embryos comparing control (w1118) and DHR3 mutants (DHR3G60S/Df(2R)12) Two-condition experiment, control vs. DHR3 mutant embryos. Biological replicates: 4 replicates.

OTHER RELATED OMICS DATASETS IN: PRJNA120283

ORGANISM(S): Drosophila melanogaster  

SUBMITTER: Carl S Thummel  Anne-Françoise Ruaud  Carl Thummel 

PROVIDER: E-GEOD-18577 | ArrayExpress | 2010-05-19

SECONDARY ACCESSION(S): GSE18577PRJNA120283

REPOSITORIES: GEO, ArrayExpress

Dataset's files

Source:
Action DRS
E-GEOD-18577.README.txt Txt
E-GEOD-18577.eSet.r Other
E-GEOD-18577.idf.txt Idf
E-GEOD-18577.processed.1.zip Processed
E-GEOD-18577.raw.1.zip Raw
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Publications

The Drosophila nuclear receptors DHR3 and betaFTZ-F1 control overlapping developmental responses in late embryos.

Ruaud Anne-Françoise AF   Lam Geanette G   Thummel Carl S CS  

Development (Cambridge, England) 20100101 1


Studies of the onset of metamorphosis have identified an ecdysone-triggered transcriptional cascade that consists of the sequential expression of the transcription-factor-encoding genes DHR3, betaFTZ-F1, E74A and E75A. Although the regulatory interactions between these genes have been well characterized by genetic and molecular studies over the past 20 years, their developmental functions have remained more poorly understood. In addition, a transcriptional sequence similar to that observed in pr  ...[more]

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