Transcriptomics

Dataset Information

5

Transcription profiling of rat adult and neonate dorsal horn after sciatic nerve injury


ABSTRACT: As rats do not develop neuropathic pain like hypersensitivity as neonates post nerve injury but do as adults we have used these arrays to help define the processes involved in this process. Rat spinal cord (ipsilateral dorsal horn) was assayed 7 days post SNI injury to the sciatic nerve relative to sham injury. Two age groups of animals were tested Neonates (P10) and Adult (8-12wks). Experiment Overall Design: Six biologically indepenedent arrays were hybridized per assay point. Dorsal horn total RNA was prepared using standard Affymetrix protocols. Affymetrix Rat Expression 230A array used.

INSTRUMENT(S): 418 [Affymetrix]

ORGANISM(S): Rattus norvegicus  

SUBMITTER: Caroline Emma Johnston  

PROVIDER: E-GEOD-18803 | ArrayExpress | 2009-11-10

SECONDARY ACCESSION(S): GSE18803PRJNA121215

REPOSITORIES: GEO, ArrayExpress

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