Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Stefano Caramuta Suzanne Egyházi
PROVIDER: E-GEOD-19387 | ArrayExpress | 2010-04-21
SECONDARY ACCESSION(S): GSE19387PRJNA121743
REPOSITORIES: GEO, ArrayExpress
Caramuta Stefano S Egyházi Suzanne S Rodolfo Monica M Witten Daniela D Hansson Johan J Larsson Catharina C Lui Weng-Onn WO
The Journal of investigative dermatology 20100401 8
Malignant cutaneous melanoma is a highly aggressive form of skin cancer. Despite improvements in early melanoma diagnosis, the 5-year survival rate remains low in advanced disease. Therefore, novel biomarkers are urgently needed to devise new means of detection and treatment. In this study, we aimed to improve our understanding of microRNA (miRNA) deregulation in melanoma development and their impact on patient survival. Global miRNA expression profiles of a set of melanoma lymph node metastases ...[more]