Dataset Information


NINJA connects JAZ proteins to the co-repressor TOPLESS

ABSTRACT: NINJA (At4g28910) and TOPLESS proteins function as negative regulators of jasmonate responses. Our results point to TPL proteins as general co-repressors that affect multiple signalling pathways through the interaction with specific adaptor proteins. This new insight reveals how stress- and growth-related signalling cascades use common molecular mechanisms to regulate gene expression in plants. Two-condition experiment, Col-0 vs. plants silencing NINJA (RNAi-NINJA) and both Col-0 vs RNAi NINJA treated with coronatine . Biological replicates: 4 control replicates untreated , 4 RNAi NINJA untreated replicates, 4 control treated replicates and 4 RNAi NINJA treated replicates

ORGANISM(S): Arabidopsis thaliana  

SUBMITTER: Gloria García-Casado   Geert De Jaeger  Roberto Solano  Alain Goossens  Amparo C Pérez  Laurens Pauwels  Robin Vanden Bossche  Jeff Long  Erwin Witters  José M Chico  Gemma F Barbero  Wim Grunewald  Sofie Tilleman  Jan Geerinck  Dirk Inzé  Jared Sewell  Gloria Garcia Casado  Eduardo Gil 

PROVIDER: E-GEOD-19455 | ArrayExpress | 2010-04-05



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Jasmonoyl-isoleucine (JA-Ile) is a plant hormone that regulates a broad array of plant defence and developmental processes. JA-Ile-responsive gene expression is regulated by the transcriptional activator MYC2 that interacts physically with the jasmonate ZIM-domain (JAZ) repressor proteins. On perception of JA-Ile, JAZ proteins are degraded and JA-Ile-dependent gene expression is activated. The molecular mechanisms by which JAZ proteins repress gene expression remain unknown. Here we show that th  ...[more]

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