Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Brian Tuch Rebecca R Laborde David I Smith
PROVIDER: E-GEOD-20116 | ArrayExpress | 2010-02-25
SECONDARY ACCESSION(S): GSE20116SRP002009PRJNA124251
REPOSITORIES: GEO, ArrayExpress, ENA
PloS one 20100219 2
Due to growing throughput and shrinking cost, massively parallel sequencing is rapidly becoming an attractive alternative to microarrays for the genome-wide study of gene expression and copy number alterations in primary tumors. The sequencing of transcripts (RNA-Seq) should offer several advantages over microarray-based methods, including the ability to detect somatic mutations and accurately measure allele-specific expression. To investigate these advantages we have applied a novel, strand-spe ...[more]