Transcriptomics

Dataset Information

9

T cell genes regulated by retinoic acid


ABSTRACT: This is to determine the T cell genes regulated by retinoic acid. 3 groups of CD4+ T cells (control, RA and Ro) 2 arrays were used for each group

ORGANISM(S): Mus musculus  

SUBMITTER: Benjamin J Ulrich   Ann Feil  Seung G Kang  chang Kim  Chang H Kim 

PROVIDER: E-GEOD-20500 | ArrayExpress | 2011-02-14

SECONDARY ACCESSION(S): GSE20500GDS3840PRJNA125081

REPOSITORIES: GEO, ArrayExpress

altmetric image

Publications

Complementary roles of retinoic acid and TGF-β1 in coordinated expression of mucosal integrins by T cells.

Kang S G SG   Park J J   Cho J Y JY   Ulrich B B   Kim C H CH  

Mucosal immunology 20100721 1


α(4) and β(7) integrins, such as α(4)β(1), α(4)β(7), and α(E)β(7), are major integrins required for migration of leukocytes into mucosal tissues. The mechanisms responsible for coordinated expression of these three integrins have been poorly elucidated to date. We report that expression of the Itg-α(4) subunit by both CD4(+) and CD8(+) T cells requires the retinoic acid signal. In contrast, transcription of Itg-α(E) genes is induced by the transforming growth factor-β1 (TGFβ1) signal. Expression  ...[more]

Similar Datasets

2013-02-26 | E-GEOD-34324 | ArrayExpress
2012-03-02 | E-GEOD-22025 | ArrayExpress
2013-08-25 | E-GEOD-36569 | ArrayExpress
2014-08-28 | E-GEOD-60234 | ArrayExpress
2010-07-09 | E-GEOD-22577 | ArrayExpress
2014-01-21 | E-GEOD-39457 | ArrayExpress
2014-05-01 | E-GEOD-34755 | ArrayExpress
2014-04-24 | E-GEOD-47988 | ArrayExpress
2014-04-24 | E-GEOD-55244 | ArrayExpress
2010-05-06 | E-GEOD-14518 | ArrayExpress