Transcriptomics

Dataset Information

3

Escherichia coli K-12: luxS mutant LW12 vs. wild type W3110


ABSTRACT: Transcripitonal profiling of Escherichia coli K-12 comparing luxS mutant LW12 with wild type W3110 One-condition experiment, luxS mutant LW12 vs. wild type W3110

ORGANISM(S): Escherichia coli  

SUBMITTER: Hua Ling   A R Kang  Matthew C Wook 

PROVIDER: E-GEOD-20606 | ArrayExpress | 2010-11-11

SECONDARY ACCESSION(S): GSE20606PRJNA124781

REPOSITORIES: GEO, ArrayExpress

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Publications

The absence of the luxS gene increases swimming motility and flagella synthesis in Escherichia coli K12.

Ling Hua H   Kang Aram A   Tan Mui Hua MH   Qi Xiaobao X   Chang Matthew Wook MW  

Biochemical and biophysical research communications 20100925 4


Despite the significant role of S-ribosylhomocysteinase (LuxS) in the activated methyl cycle pathway and quorum sensing, the connectivity between luxS and other cellular functions remains incomplete. Herein, we show that luxS deletion significantly increases swimming motility and flagella synthesis in Escherichia coli K12 using motility, transcriptome, and scanning electron microscopy assays. Further, based on the transcriptome and network component analyses, and known regulatory relations, we p  ...[more]

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