Dataset Information


Expression profiling of human adipose stromal cell (hASC) adipogenesis

ABSTRACT: Human abdominal adipose tissue was obtained with informed consent from a 33-year old Caucasian female (BMI = 32.96 Kg/m2) undergoing lipoaspiration. Adipose stromal cells (hASCs) were isolated and differentiated into adipocytes in vitro. Two technical replicates from 9 time points realtive to induction of adipogenesis (day 0). Also, two technical replicated from pre-adipocytes (day -2) grown without FGF. Two individual replicates (day 1 and day 7) were removed due to failed hybridizations.

ORGANISM(S): Homo sapiens  

SUBMITTER: Tarjei S Mikkelsen   Zhao Xu  Evan D Rosen  Jeffery M Gimble  Eric S Lander 

PROVIDER: E-GEOD-20697 | ArrayExpress | 2010-09-30



altmetric image


Comparative epigenomic analysis of murine and human adipogenesis.

Mikkelsen Tarjei S TS   Xu Zhao Z   Zhang Xiaolan X   Wang Li L   Gimble Jeffrey M JM   Lander Eric S ES   Rosen Evan D ED  

Cell 20101001 1

We report the generation and comparative analysis of genome-wide chromatin state maps, PPARγ and CTCF localization maps, and gene expression profiles from murine and human models of adipogenesis. The data provide high-resolution views of chromatin remodeling during cellular differentiation and allow identification of thousands of putative preadipocyte- and adipocyte-specific cis-regulatory elements based on dynamic chromatin signatures. We find that the specific locations of most such elements d  ...[more]

Similar Datasets

2010-09-30 | E-GEOD-20699 | ArrayExpress
2010-09-30 | GSE20699 | GEO
| GSE20697 | GEO
2011-05-31 | E-GEOD-27912 | ArrayExpress
2011-05-31 | E-GEOD-27949 | ArrayExpress
2013-12-01 | E-MTAB-1906 | ArrayExpress
2018-12-12 | E-MTAB-6728 | ArrayExpress
| GSE77532 | GEO
2013-02-02 | E-GEOD-44000 | ArrayExpress
2016-07-01 | E-GEOD-80816 | ArrayExpress