Ontology highlight
ABSTRACT:
OTHER RELATED OMICS DATASETS IN: PRJNA126135
ORGANISM(S): Homo Sapiens
DISEASE(S): Control,Dm,Replicate Control
SUBMITTER: C. R Kahn Robert Saccone Edward Mun Kenneth Cusi Mary Elizabeth Patti Lawrence J Mandarino Ralph DeFronzo Jean Finlayson Sangeeta Kashyap Sarah Crunkhorn Maura Costello Isaac Kohane Edwin J Landaker Atul J Butte Allison B Goldfine Yoshinori Miyazaki Reachel Berria Mary E Patti
PROVIDER: E-GEOD-21340 | ArrayExpress | 2010-04-27
SECONDARY ACCESSION(S): GSE21340PRJNA126135
REPOSITORIES: GEO, ArrayExpress
Action | DRS | |||
---|---|---|---|---|
E-GEOD-21340.README.txt | Txt | |||
E-GEOD-21340.eSet.r | Other | |||
E-GEOD-21340.idf.txt | Idf | |||
E-GEOD-21340.processed.1.zip | Processed | |||
E-GEOD-21340.raw.1.zip | Raw |
Items per page: 1 - 5 of 6 |
Proceedings of the National Academy of Sciences of the United States of America 20030627 14
Type 2 diabetes mellitus (DM) is characterized by insulin resistance and pancreatic beta cell dysfunction. In high-risk subjects, the earliest detectable abnormality is insulin resistance in skeletal muscle. Impaired insulin-mediated signaling, gene expression, glycogen synthesis, and accumulation of intramyocellular triglycerides have all been linked with insulin resistance, but no specific defect responsible for insulin resistance and DM has been identified in humans. To identify genes potenti ...[more]