Transcriptomics,Multiomics

Dataset Information

10

Biobank of Karolinska Endarterectomy (BiKE)


ABSTRACT: A biobank collection of carotid plaque samples taken from patients undergoing endarterectomy operations. Samples from carotid plaques and peripheral blood mononuclear cells in a setup with clinical registry data collection. See PMID 22371308 for further details.

OTHER RELATED OMICS DATASETS IN: PRJNA126209

ORGANISM(S): Homo sapiens  

SUBMITTER: Hanna E Agardh   Johan Ekstrand  Anders Gabrielsen  Lasse Folkersen  Gabrielle Paulsson-Berne  Jonas Persson  Göran K Hansson  Ulf Hedin 

PROVIDER: E-GEOD-21545 | ArrayExpress | 2012-03-27

SECONDARY ACCESSION(S): GSE21545PRJNA126209

REPOSITORIES: GEO, ArrayExpress

Dataset's files

Source:
Action DRS
E-GEOD-21545.README.txt Txt
E-GEOD-21545.eSet.r Other
E-GEOD-21545.idf.txt Idf
E-GEOD-21545.processed.1.zip Processed
E-GEOD-21545.raw.1.zip Raw
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Publications

Prediction of ischemic events on the basis of transcriptomic and genomic profiling in patients undergoing carotid endarterectomy.

Folkersen Lasse L   Persson Jonas J   Ekstrand Johan J   Agardh Hanna E HE   Hansson Göran K GK   Gabrielsen Anders A   Hedin Ulf U   Paulsson-Berne Gabrielle G  

Molecular medicine (Cambridge, Mass.) 20120509


Classic risk factors, including age, smoking, serum cholesterol, diabetes and blood pressure, constitute the basis of present risk prediction models but fail to identify all individuals at risk. The objective of this study was to investigate if genomic and transcriptional patterns improve prediction of ischemic events in patients with established carotid artery disease. Genotype and gene expression profiles were obtained from carotid plaque tissue (n = 126) and peripheral blood mononuclear cells  ...[more]

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