Genomics,Multiomics

Dataset Information

3

E. coli K-12 mutant yjgI biofilm vs. wild type biofilm


ABSTRACT: The gene expression of glasswool biofilm cells in E. coli yjgI mutant vs. E. coli wild type strain in LB. Strains: E. coli K12 BW25113 wild type, yjgI mutant Medium: LB Biofilm grown on glass wool Time: 15 h Cell type: biofilm

OTHER RELATED OMICS DATASETS IN: PRJNA128971

ORGANISM(S): Escherichia coli  

SUBMITTER: Qun Ma   Thomas K Wood  Thomas Wood 

PROVIDER: E-GEOD-22057 | ArrayExpress | 2011-05-29

SECONDARY ACCESSION(S): GSE22057PRJNA128971

REPOSITORIES: GEO, ArrayExpress

Dataset's files

Source:
Action DRS
E-GEOD-22057.idf.txt Idf
E-GEOD-22057.processed.1.zip Processed
E-GEOD-22057.raw.1.zip Raw
E-GEOD-22057.sdrf.txt Txt
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Publications

Engineering a novel c-di-GMP-binding protein for biofilm dispersal.

Ma Qun Q   Yang Zhonghua Z   Pu Mingming M   Peti Wolfgang W   Wood Thomas K TK  

Environmental microbiology 20101108 3


Bacteria prefer to grow attached to themselves or an interface, and it is important for an array of applications to make biofilms disperse. Here we report simultaneously the discovery and protein engineering of BdcA (formerly YjgI) for biofilm dispersal using the universal signal 3,5-cyclic diguanylic acid (c-di-GMP). The bdcA deletion reduced biofilm dispersal, and production of BdcA increased biofilm dispersal to wild-type level. Since BdcA increases motility and extracellular DNA production w  ...[more]

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