Transcriptomics

Dataset Information

7

Gene expression profiling of the early-stage CD34+ differentiation process


ABSTRACT: To better understand the early events regulating lineage-specific hematopoietic differentiation, we analyzed the transcriptional profiles of CD34+ human hematopoietic stem and progenitor cells (HSPCs) subjected to differentiation stimulus. CD34+ cells were cultured for 12 and 40 hours in liquid cultures with supplemented media favoring myeloid or erythroid commitment. Serial analysis of gene expression (SAGE) was employed to generate four independent libraries. CD34+ Hematopoietic Stem Progenitor Cells with no differentiation stimulus were used as a control library.

ORGANISM(S): Homo sapiens  

SUBMITTER: Dalila L Zanette   Marco A Zago  Wilson A Silva Jr  Greice A Molfetta  Daniel Guariz Pinheiro  Rodrigo A Panepucci  Daniel G Pinheiro 

PROVIDER: E-GEOD-22092 | ArrayExpress | 2010-12-01

SECONDARY ACCESSION(S): GSE22092PRJNA128827

REPOSITORIES: GEO, ArrayExpress

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