Transcriptomics

Dataset Information

4

Expression data from CD71+ cells from the bone marrow of WT, CD70TG, IFNg-/- and CD70TG*IFNg-/- mice.


ABSTRACT: CD70TG mice are a model for sterile chronic immune activation and develop Anemia of Inflammation, which is dependent on the production of Ifng by effector CD4 and CD8 T cells. We used microarrays to identify Ifng-dependent differentially expressed genes that could account for the erythropoietic defect. CD71+ cells were MACS-enriched from the bone marrow of WT, CD70TG, IFNg-/- and CD70TG*IFNg-/- male mice of 10-12 weeks of age (3 mice per genotype group).

ORGANISM(S): Mus musculus  

SUBMITTER: Martijn A Nolte   Laura Gutiérrez  Laura Gutierrez 

PROVIDER: E-GEOD-22656 | ArrayExpress | 2011-07-31

SECONDARY ACCESSION(S): GSE22656PRJNA128025

REPOSITORIES: GEO, ArrayExpress

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