Transcriptomics

Dataset Information

63

15.5dpc Ureteric tree cells Vs rest


ABSTRACT: Triplicate pairwise comparsion of FACS sorted GFP+ve Vs GFP-ve cells from the kidneys of the HoxB7-GFP transgenic mice on compugen 22K mouse arrays. HoxB7-GFP mice express GFP in the ureteric tree and its derivatives while the metanephric mesenchyme, interstitium, developing vasculature etc do not.

ORGANISM(S): Mus musculus  

SUBMITTER: Sean M Grimmond   Darrin F Taylor 

PROVIDER: E-GEOD-2281 | ArrayExpress | 2010-06-09

SECONDARY ACCESSION(S): GSE2281PRJNA91335

REPOSITORIES: GEO, ArrayExpress

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Publications

Temporal and spatial transcriptional programs in murine kidney development.

Challen G   Gardiner B   Caruana G   Kostoulias X   Martinez G   Crowe M   Taylor DF   Bertram J   Little M   Grimmond SM  

Physiological genomics 20050705 2


We have performed a systematic temporal and spatial expression profiling of the developing mouse kidney using Compugen long-oligonucleotide microarrays. The activity of 18,000 genes was monitored at 24-h intervals from 10.5-day-postcoitum (dpc) metanephric mesenchyme (MM) through to neonatal kidney, and a cohort of 3,600 dynamically expressed genes was identified. Early metanephric development was further surveyed by directly comparing RNA from 10.5 vs. 11.5 vs. 13.5dpc kidneys. These data showe  ...[more]

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