Transcriptomics

Dataset Information

6

Effect of polymorphic Y chromosomes on XXY females


ABSTRACT: see publication, arrays from 4 XXY genotypes containing polymorphic Y chromosomes Dye swaps, loop design.

ORGANISM(S): Drosophila melanogaster  

SUBMITTER: Bernardo Lemos   Alan T Branco 

PROVIDER: E-GEOD-23612 | ArrayExpress | 2010-10-02

SECONDARY ACCESSION(S): GSE23612PRJNA129955

REPOSITORIES: GEO, ArrayExpress

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Publications

Epigenetic effects of polymorphic Y chromosomes modulate chromatin components, immune response, and sexual conflict.

Lemos Bernardo B   Branco Alan T AT   Hartl Daniel L DL  

Proceedings of the National Academy of Sciences of the United States of America 20100823 36


Genetic conflicts between sexes and generations provide a foundation for understanding the functional evolution of sex chromosomes and sexually dimorphic phenotypes. Y chromosomes of Drosophila contain multi-megabase stretches of satellite DNA repeats and a handful of protein-coding genes that are monomorphic within species. Nevertheless, polymorphic variation in heterochromatic Y chromosomes of Drosophila result in genome-wide gene expression variation. Here we show that such naturally occurrin  ...[more]

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