Transcriptomics

Dataset Information

7

Sciatic nerve FAIRE-chip and ChIP-Chip with Egr2/Krox20 and Sox10


ABSTRACT: Egr2/Krox20 and Sox10 regulate genes involved in formation of myelination in the peripheral nervous system. ChIP-chip assays were performed on rat sciatic nerve at P15, a peak timepoint of myelination. In addition, Faire was used to identify areas of open chromatin. This experiment includes a custom ChIP-chip design incorporating many genes that are dynamically regulated during peripheral nerve myelination. Two antibodies were used for Egr2, Abcam and Covance PRB-236P. Egr2 and Sox10 ChIP samples were hybridized along with total input. In addition, FAIRE samples were hybridized relative to input DNA

ORGANISM(S): Rattus norvegicus  

SUBMITTER: Erin A Jones   John Svaren  Rajini Srinivasan 

PROVIDER: E-GEOD-23648 | ArrayExpress | 2010-10-14

SECONDARY ACCESSION(S): GSE23648PRJNA130963

REPOSITORIES: GEO, ArrayExpress

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