Transcriptomics

Dataset Information

40

Expression data from 5 day old Arabidopsis thaliana seedlings


ABSTRACT: Upon induction of DNA damage Arabidopsis thaliana plants initiate a transcriptional response program governed by signalling cascades which are activated by the ATM and ATR kinases To analyse if the ATM dependent gene GMI1 (At5G24280) is involved in the regulation of the transcriptionl response, we compared the gene expression profiles of wildtype and gmi1 deficient plants upon gamma-irradiation

ORGANISM(S): Arabidopsis thaliana  

SUBMITTER: Gudrun Boehmdorfer  Dieter Schweizer   Reinhard Brunmeir   David P Kreil    

PROVIDER: E-GEOD-23892 | ArrayExpress| 2012-03-27

SECONDARY ACCESSION(S): GSE23892PRJNA130439

REPOSITORIES: GEO, ArrayExpress

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Publications

GMI1, a structural-maintenance-of-chromosomes-hinge domain-containing protein, is involved in somatic homologous recombination in Arabidopsis.

Böhmdorfer Gudrun G   Schleiffer Alexander A   Brunmeir Reinhard R   Ferscha Stefan S   Nizhynska Viktoria V   Kozák Jaroslav J   Angelis Karel J KJ   Kreil David P DP   Schweizer Dieter D  

The Plant journal : for cell and molecular biology 20110520 3


DNA double-strand breaks (DSBs) pose one of the most severe threats to genome integrity, potentially leading to cell death. After detection of a DSB, the DNA damage and repair response is initiated and the DSB is repaired by non-homologous end joining and/or homologous recombination. Many components of these processes are still unknown in Arabidopsis thaliana. In this work, we characterized γ-irradiation and mitomycin C induced 1 (GMI1), a member of the SMC-hinge domain-containing protein family  ...[more]

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