Ontology highlight
ABSTRACT:
OTHER RELATED OMICS DATASETS IN: PRJNA93275PRJNA91617
ORGANISM(S): Saccharomyces cerevisiae
SUBMITTER: David Johannes Clark
PROVIDER: E-GEOD-2407 | ArrayExpress | 2007-07-07
SECONDARY ACCESSION(S): GSE2407GDS1270PRJNA91617
REPOSITORIES: GEO, ArrayExpress
Action | DRS | |||
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E-GEOD-2407.README.txt | Txt | |||
E-GEOD-2407.idf.txt | Idf | |||
E-GEOD-2407.processed.1.zip | Processed | |||
E-GEOD-2407.sdrf.txt | Txt |
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Mendiratta Geetu G Eriksson Peter R PR Shen Chang-Hui CH Clark David J DJ
The Journal of biological chemistry 20060116 11
The yeast SPT10 gene encodes a putative histone acetyltransferase that binds specifically to pairs of upstream activating sequence (UAS) elements found only in the histone gene promoters. Here, we demonstrate that the DNA-binding domain of Spt10p is located between residues 283 and 396 and includes a His(2)-Cys(2) zinc finger. The binding of Spt10p to the histone UAS is zinc-dependent and is disabled by a zinc finger mutation (C388S). The isolated DNA-binding domain binds to single histone UAS e ...[more]