Transcriptomics

Dataset Information

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Mouse embryo heart, e10.5 AVC: Control vs. Tbx3 hypomorphic mutant


ABSTRACT: Transcriptional profiling of the atrioventricular canal from e10.5 mouse hearts comparing wild-type control with Tbx3 GH/N hypomorphic mutant microdissected tissue. The goal was to identify direct and indirect targets of the transcription factor Tbx3, because Tbx3 is expressed in the AVC and hypomorphs develop embryonic AV conduction block at e12.5. Two-condition experiment, wild-type control and Tbx3 mutant AVC tissue. Tissue from 5 hearts was pooled to make each sample. Biological replicates: 4.

ORGANISM(S): Mus musculus  

SUBMITTER: Deborah U Frank   Anne M Moon  Deborah Frank 

PROVIDER: E-GEOD-24122 | ArrayExpress | 2011-04-01

SECONDARY ACCESSION(S): GSE24122PRJNA130061

REPOSITORIES: GEO, ArrayExpress

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