Transcriptomics

Dataset Information

53

Large intergenic non-coding RNAs as novel modulators of reprogramming


ABSTRACT: This SuperSeries is composed of the following subset Series: GSE23968: Large intergenic non-coding RNAs as novel modulators of reprogramming: ESCs, fibroblast, and fibroblast-derived iPSC (gene expression) GSE23970: Large intergenic non-coding RNAs as novel modulators of reprogramming: human embryonic stem cells, CD34+ cells, and CD34+ derived induced pluripotent stem cells (LincRNA expression) GSE23973: Large intergenic non-coding RNAs as novel modulators of reprogramming: siRNA (gene expression) GSE24181: Large intergenic non-coding RNAs as novel modulators of reprogramming: human embryonic stem cells, fibroblasts, and fibroblast-derived induced pluripotent stem cells (LincRNA expression) Refer to individual Series

ORGANISM(S): Homo sapiens  

SUBMITTER: Nataly Moran Cabili   

PROVIDER: E-GEOD-24182 | ArrayExpress | 2012-03-27

SECONDARY ACCESSION(S): GSE24182PRJNA130107

REPOSITORIES: GEO, ArrayExpress

altmetric image

Publications


The conversion of lineage-committed cells to induced pluripotent stem cells (iPSCs) by reprogramming is accompanied by a global remodeling of the epigenome, resulting in altered patterns of gene expression. Here we characterize the transcriptional reorganization of large intergenic non-coding RNAs (lincRNAs) that occurs upon derivation of human iPSCs and identify numerous lincRNAs whose expression is linked to pluripotency. Among these, we defined ten lincRNAs whose expression was elevated in iP  ...[more]

Similar Datasets

| PRJNA130107 | ENA
| PRJNA133715 | ENA
| PRJNA133201 | ENA
| PRJNA133191 | ENA
| PRJNA133203 | ENA
2014-12-10 | E-GEOD-56567 | ArrayExpress
2014-08-09 | E-GEOD-54848 | ArrayExpress
| GSE57967 | GEO
2014-12-10 | E-GEOD-56568 | ArrayExpress
2012-03-27 | E-GEOD-24181 | ArrayExpress