Genomics

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Nucleosome repositioning-coupled expression divergence between species


ABSTRACT: We describe the genome-wide nucleosome profiles for S. bayanus under standard conditions Nucleosomes from S. bayanus was isolated and sequenced using the Illumina GAII platform.

ORGANISM(S): Saccharomyces bayanus  

SUBMITTER: Amy Caudy   Vicky Yao  Maitreya Dunham  Marinella Gebbia  Corey Nislow  Kyle Tsui  Yuanfang Guan  Olga Troyanskaya 

PROVIDER: E-GEOD-24356 | ArrayExpress | 2011-11-10

SECONDARY ACCESSION(S): SRP003624GSE24356PRJNA132811

REPOSITORIES: GEO, ArrayExpress, ENA

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Publications

Nucleosome-coupled expression differences in closely-related species.

Guan Yuanfang Y   Yao Victoria V   Tsui Kyle K   Gebbia Marinella M   Dunham Maitreya J MJ   Nislow Corey C   Troyanskaya Olga G OG  

BMC genomics 20110926


Genome-wide nucleosome occupancy is negatively related to the average level of transcription factor motif binding based on studies in yeast and several other model organisms. The degree to which nucleosome-motif interactions relate to phenotypic changes across species is, however, unknown.We address this challenge by generating nucleosome positioning and cell cycle expression data for Saccharomyces bayanus and show that differences in nucleosome occupancy reflect cell cycle expression divergence  ...[more]

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