Transcriptomics

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Human Fetal and Adult Peripheral Naïve CD4+ T cells and CD4+CD25+ Treg cells


ABSTRACT: We compared differences in fetal and adult T cells by performing whole genome profiling on sort-purified T cells (naïve CD4+ and Treg cells) from human fetal specimens (18-22 gestational weeks) and adult specimens (age 25-40 years old). Fetal and Adult Naïve CD4+ T cells phenotype: CD3+CD4+CD45RA+CCR7+CD27+, Fetal and Adult CD4+CD25+ Treg phenotype: CD3+CD4+CD25bright Four different groups were analyzed: Fetal Naïve CD4+ T cells, Adult Naïve CD4+ T cells, Fetal Treg cells, Adult Treg cells. For each group three independent donors were analyzed.

ORGANISM(S): Homo sapiens  

SUBMITTER: Jeff E Mold   Shivkumar Venkatasubrahmanyam  Joseph M McCune  Jakob Michaelsson  Jeff E. Mold  Jose M Rivera  Sofiya A Galkina  Kenneth Weinberg  Cheryl A Stoddart  Trevor D Burt 

PROVIDER: E-GEOD-25087 | ArrayExpress | 2010-12-17

SECONDARY ACCESSION(S): GSE25087PRJNA142745

REPOSITORIES: GEO, ArrayExpress

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