Transcriptomics

Dataset Information

4

Expression Profiling of Formalin-Fixed Parafin-Embedded Primary Breast Tumors DASL Cancer Panel


ABSTRACT: HER2-positive and HER2-negative samples are compared within this DASL Cancer Panel Platform Two-class comparison

ORGANISM(S): Homo sapiens  

SUBMITTER: Beiyun Chen   Amylou C Dueck  Wilma L Lingle  Robert B Jenkins  Monica M Reinholz  Craig S April  Julie M Cunningham  Yan W Asmann  Michael A Zschunke  Edith A Perez  Jian-Bing Fan  S K Anderson  Ann E McCullough  Jin Jen  Jeanette E Eckel-Passow  Keith Anderson  Ann L Oberg  Eliza Wickham-Garcia 

PROVIDER: E-GEOD-25231 | ArrayExpress | 2010-12-20

SECONDARY ACCESSION(S): GSE25231PRJNA142529

REPOSITORIES: GEO, ArrayExpress

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Publications


The cDNA-mediated Annealing, extension, Selection and Ligation (DASL) assay has become a suitable gene expression profiling system for degraded RNA from paraffin-embedded tissue. We examined assay characteristics and the performance of the DASL 502-gene Cancer Panel v1 (1.5K) and 24,526-gene panel (24K) platforms at differentiating nine human epidermal growth factor receptor 2- positive (HER2+) and 11 HER2-negative (HER2-) paraffin-embedded breast tumors.Bland-Altman plots and Spearman correlati  ...[more]

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