Dataset Information


Expression Profiling of Formalin-Fixed Parafin-Embedded Primary Breast Tumors DASL Cancer Panel

ABSTRACT: HER2-positive and HER2-negative samples are compared within this DASL Cancer Panel Platform Two-class comparison

ORGANISM(S): Homo sapiens  

SUBMITTER: Beiyun Chen  Amylou C Dueck   Wilma L Lingle   Robert B Jenkins   Monica M Reinholz   Craig S April   Julie M Cunningham   Yan W Asmann   Michael A Zschunke   Edith A Perez   Jian-Bing Fan   S K Anderson   Ann E McCullough   Jin Jen   Jeanette E Eckel-Passow   Keith Anderson   Ann L Oberg   Eliza Wickham-Garcia    

PROVIDER: E-GEOD-25231 | ArrayExpress | 2012-06-26



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The cDNA-mediated Annealing, extension, Selection and Ligation (DASL) assay has become a suitable gene expression profiling system for degraded RNA from paraffin-embedded tissue. We examined assay characteristics and the performance of the DASL 502-gene Cancer Panel v1 (1.5K) and 24,526-gene panel (24K) platforms at differentiating nine human epidermal growth factor receptor 2- positive (HER2+) and 11 HER2-negative (HER2-) paraffin-embedded breast tumors.Bland-Altman plots and Spearman correlati  ...[more]

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