Transcriptomics

Dataset Information

4

Expression Profiling of Formalin-Fixed Parafin-Embedded Primary Breast Tumors Whole Genome DASL


ABSTRACT: HER2-positive and HER2-negative samples are compared within this Whole Genome Platform Two-class comparison

ORGANISM(S): Homo sapiens  

SUBMITTER: Beiyun Chen   Amylou C Dueck  Wilma L Lingle  Robert B Jenkins  Monica M Reinholz  Craig S April  Julie M Cunningham  Michael A Zschunke  Yan W Asmann  Jian-Bing Fan  Edith A Perez  Ann E McCullough  S K Anderson  Jin Jen  Jeanette E Eckel-Passow  Keith Anderson  Ann L Oberg  Eliza Wickham-Garcia 

PROVIDER: E-GEOD-25233 | ArrayExpress | 2010-12-20

SECONDARY ACCESSION(S): GSE25233PRJNA142531

REPOSITORIES: GEO, ArrayExpress

Dataset's files

Source:
Action DRS
E-GEOD-25233.README.txt Txt
E-GEOD-25233.idf.txt Idf
E-GEOD-25233.processed.1.zip Processed
E-GEOD-25233.sdrf.txt Txt
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Publications


<h4>Background</h4>The cDNA-mediated Annealing, extension, Selection and Ligation (DASL) assay has become a suitable gene expression profiling system for degraded RNA from paraffin-embedded tissue. We examined assay characteristics and the performance of the DASL 502-gene Cancer Panel v1 (1.5K) and 24,526-gene panel (24K) platforms at differentiating nine human epidermal growth factor receptor 2- positive (HER2+) and 11 HER2-negative (HER2-) paraffin-embedded breast tumors.<h4>Methods</h4>Bland-  ...[more]

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