Dataset Information


Comparative analyses of transcriptome during skeletal muscle development between pig breeds differing in muscle growth rate by deep-sequencing

ABSTRACT: Obese and lean pig show breed-specific traits in muscle growth and meat quality. However, the mechanisms underlying remains unclear. Here, we reported the first genome-wide muscle development research from embryonic to 6 months old between Lantang (obese) and Landrace (lean) using Solexa/Illumina’s Genome Analyzer. We obtained 4.22±0.9×107 total reads per sample with approximately 5×106 distinct tags. Filtered adaptor tags, empty reads, low quality tags and tags of copy number =1, we obtained 3.84±0.9×107 clean total tags with 1.5±0.5×106 clean distinct tags. 20 libraries of longissimus muscle samples were sequenced in Lantang and Landrace at days 35, 49, 63, 77, 91 prenatal and 2, 28, 90, 120, 180 postnatal days.

ORGANISM(S): Sus scrofa  

SUBMITTER: Wen Gong   Anning Li  Dolin Mo  Yaosheng Chen  Xiao Zhao  Shuqi Xiao  zhao xiao  Yue Zhang 

PROVIDER: E-GEOD-25406 | ArrayExpress | 2012-06-18



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Comparative analyses by sequencing of transcriptomes during skeletal muscle development between pig breeds differing in muscle growth rate and fatness.

Zhao Xiao X   Mo Delin D   Li Anning A   Gong Wen W   Xiao Shuqi S   Zhang Yue Y   Qin Limei L   Niu Yuna Y   Guo Yunxue Y   Liu Xiaohong X   Cong Peiqing P   He Zuyong Z   Wang Chong C   Li Jiaqi J   Chen Yaosheng Y  

PloS one 20110526 5

Understanding the dynamics of muscle transcriptome during development and between breeds differing in muscle growth is necessary to uncover the complex mechanism underlying muscle development. Herein, we present the first transcriptome-wide longissimus dorsi muscle development research concerning Lantang (LT, obese) and Landrace (LR, lean) pig breeds during 10 time-points from 35 days-post-coitus (dpc) to 180 days-post-natum (dpn) using Solexa/Illumina's Genome Analyzer. The data demonstrated th  ...[more]

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