Ontology highlight
ABSTRACT:
OTHER RELATED OMICS DATASETS IN: PRJNA92121
SUBMITTER: Yipeng Wang Gaelle Rondeau
PROVIDER: E-GEOD-2655 | ArrayExpress | 2010-06-10
SECONDARY ACCESSION(S): GSE2655PRJNA92121
REPOSITORIES: GEO, ArrayExpress
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E-GEOD-2655.README.txt | Txt | |||
E-GEOD-2655.idf.txt | Idf | |||
E-GEOD-2655.processed.1.zip | Processed | |||
E-GEOD-2655.sdrf.txt | Txt |
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Rondeau Gaëlle G McClelland Michael M Nguyen Toan T Risques Rosana R Wang Yipeng Y Judex Martin M Cho Ann H AH Welsh John J
Nucleic acids research 20050624 11
Low abundance mRNAs are more difficult to examine using microarrays than high abundance mRNAs due to the effect of concentration on hybridization kinetics and signal-to-noise ratios. This report describes the use of low complexity representations (LCRs) of mRNA as the targets for cDNA microarrays. Individual sequences in LCRs are more highly represented than in the mRNA populations from which they are derived, leading to favorable hybridization kinetics. LCR targets permit the measurement of abu ...[more]