Transcriptomics

Dataset Information

5

Impact of Visceral Fat on Gene Expression Profile in Peripheral Blood Cells


ABSTRACT: We profiled gene expression in peripheral blood cells from 28 obese patients by microarray analysis and visceral fat accumulation caused the gene expression proliles especially in circadian rhythm, inflammation, oxidative stress, and immune response. Obesity was defined as body mass index (BMI) greater than 25 kg/m2 according to the Japanese criteria and visceral fat area (VFA) was estimated by abdominal bioelectrical impedance analysis. Subjects with type 1 diabetes mellitus, autoimmune diseases, malignant diseases, and infectious diseases were excluded. Patients treated with statin and/or thiazolidinediones were also excluded.

ORGANISM(S): Homo sapiens  

SUBMITTER: Seiji Nakamura   Ken-ichi Matsubara  Tohru Funahashi  Masaya Yamaoka  Norikazu Maeda  Iichiro Shimomura 

PROVIDER: E-GEOD-28038 | ArrayExpress | 2014-01-01

SECONDARY ACCESSION(S): GSE28038PRJNA137947

REPOSITORIES: GEO, ArrayExpress

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