Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Leslie Ingram-drake
PROVIDER: E-GEOD-2814 | ArrayExpress | 2006-07-26
SECONDARY ACCESSION(S): GSE2814PRJNA92415
REPOSITORIES: GEO, ArrayExpress
van Nas Atila A Ingram-Drake Leslie L Sinsheimer Janet S JS Wang Susanna S SS Schadt Eric E EE Drake Thomas T Lusis Aldons J AJ
Genetics 20100503 3
By treating the transcript abundance as a quantitative trait, gene expression can be mapped to local or distant genomic regions relative to the gene encoding the transcript. Local expression quantitative trait loci (eQTL) generally act in cis (that is, control the expression of only the contiguous structural gene), whereas distal eQTL act in trans. Distal eQTL are more difficult to identify with certainty due to the fact that significant thresholds are very high since all regions of the genome m ...[more]