Ontology highlight
ABSTRACT:
OTHER RELATED OMICS DATASETS IN: PRJNA139353
ORGANISM(S): Mus musculus
SUBMITTER: Y Watanabe H Hosokawa A Onodera T Nakayama S Sugano S Horiuchi Atsushi Onodera T Tanaka Y Suzuki
PROVIDER: E-GEOD-28292 | ArrayExpress | 2011-03-31
SECONDARY ACCESSION(S): SRP007894GSE28292PRJNA139353
REPOSITORIES: GEO, ArrayExpress, ENA
Action | DRS | |||
---|---|---|---|---|
E-GEOD-28292.hyb.sdrf.txt | Txt | |||
E-GEOD-28292.idf.txt | Idf | |||
E-GEOD-28292.processed.1.zip | Processed | |||
E-GEOD-28292.processed.2.zip | Processed | |||
E-GEOD-28292.processed.3.zip | Processed |
Items per page: 1 - 5 of 11 |
Journal of immunology (Baltimore, Md. : 1950) 20110502 11
Differentiation of naive CD4 T cells into Th2 cells is accompanied by chromatin remodeling and increased expression of a set of Th2-specific genes, including those encoding Th2 cytokines. IL-4-mediated STAT6 activation induces high levels of transcription of GATA3, a master regulator of Th2 cell differentiation, and enforced expression of GATA3 induces Th2 cytokine expression. However, it remains unclear whether the expression of other Th2-specific genes is induced directly by GATA3. A genome-wi ...[more]