Note that files GSM62732.CEL and GSM62733.CEL, and files GSM62730.CEL and GSM62739.CEL as downloaded from GEO contain identical data.
INSTRUMENT(S): 418 [Affymetrix]
ORGANISM(S): Rattus norvegicus
TISSUE(S): Liver, Kidney
SUBMITTER: James Holzwarth
REPOSITORIES: GEO, ArrayExpress
Toxicological sciences : an official journal of the Society of Toxicology 20051026 1
Ochratoxin A (OTA) is a mycotoxin occurring naturally in a wide range of food commodities. In animals, it has been shown to cause a variety of adverse effects, nephrocarcinogenicity being the most prominent. Because of its high toxic potency and the continuous exposure of the human population, OTA has raised public health concerns. There is significant debate on how to use the rat carcinogenicity data to assess the potential risk to humans. In this context, the question of the mechanism of actio ...[more]