Dataset Information


Transcription profiling time series of Rattus norvegicus liver and kidney samples from animals treated with ochratoxin A and controls

ABSTRACT: Ochratoxin A gene expression profiling in liver and kidney, with time points of exposure from 7 days to 12 months Experiment Overall Design: three replicates for each timepoint measured, control and ochratoxin A treated for both liver and kidney.

Note that files GSM62732.CEL and GSM62733.CEL, and files GSM62730.CEL and GSM62739.CEL as downloaded from GEO contain identical data.

INSTRUMENT(S): 418 [Affymetrix]

ORGANISM(S): Rattus norvegicus  

TISSUE(S): Liver, Kidney

SUBMITTER: James Holzwarth  

PROVIDER: E-GEOD-2852 | ArrayExpress | 2007-10-10



Dataset's files

Action DRS
E-GEOD-2852.README.txt Txt
E-GEOD-2852.eSet.r Other
E-GEOD-2852.idf.txt Idf Processed Raw
Items per page:
1 - 5 of 6
altmetric image


A toxicogenomics approach to identify new plausible epigenetic mechanisms of ochratoxin a carcinogenicity in rat.

Marin-Kuan M M   Nestler S S   Verguet C C   Bezençon C C   Piguet D D   Mansourian R R   Holzwarth J J   Grigorov M M   Delatour T T   Mantle P P   Cavin C C   Schilter B B  

Toxicological sciences : an official journal of the Society of Toxicology 20051026 1

Ochratoxin A (OTA) is a mycotoxin occurring naturally in a wide range of food commodities. In animals, it has been shown to cause a variety of adverse effects, nephrocarcinogenicity being the most prominent. Because of its high toxic potency and the continuous exposure of the human population, OTA has raised public health concerns. There is significant debate on how to use the rat carcinogenicity data to assess the potential risk to humans. In this context, the question of the mechanism of actio  ...[more]

Similar Datasets

2007-10-30 | E-GEOD-2700 | ArrayExpress
1000-01-01 | S-EPMC4459765 | BioStudies
2010-01-01 | E-MEXP-2470 | ArrayExpress
2009-03-31 | E-MEXP-1761 | ArrayExpress
2019-01-01 | S-EPMC6329134 | BioStudies
2007-10-08 | E-GEOD-2582 | ArrayExpress
2008-05-24 | GSE11529 | GEO
2008-03-08 | E-GEOD-10748 | ArrayExpress
2020-01-01 | S-EPMC7145424 | BioStudies
2020-01-01 | S-EPMC7161169 | BioStudies