Transcriptomics

Dataset Information

2

EMT is the dominant program in human colon cancer (Affymetrix)


ABSTRACT: mRNA profiling data for 67 colorectal cancer at baseline Supporting data for PMID: 21251323 mRNA profiles at baseline for 67 colorectal cancer cell lines

ORGANISM(S): Homo sapiens  

SUBMITTER: Michael Nebozhyn   Michael V Nebozhyn 

PROVIDER: E-GEOD-28567 | ArrayExpress | 2011-04-25

SECONDARY ACCESSION(S): GSE28567PRJNA143015

REPOSITORIES: GEO, ArrayExpress

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Publications


Colon cancer has been classically described by clinicopathologic features that permit the prediction of outcome only after surgical resection and staging.We performed an unsupervised analysis of microarray data from 326 colon cancers to identify the first principal component (PC1) of the most variable set of genes. PC1 deciphered two primary, intrinsic molecular subtypes of colon cancer that predicted disease progression and recurrence.Here we report that the most dominant pattern of intrinsic g  ...[more]

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