Transcriptomics

Dataset Information

39

SIRT1 impact on global gene expression in the brain


ABSTRACT: We compared expression of genes in brains of SIRT1 brain-specific knockouts (BSKO) to those of wild-type littermate controls (WT). RNA was isolated from whole brain tissues of SIRT1 brain specific knockout mice (BSKO) and their wild-type littermates (WT). 3 months old males were used, four biological replicates per genotype were used. RNA was verified for integrity and processed according to Affymetrix guidelines, using kits and reagents supplied by Affymetrix. Total of 8 Affymetrix.GeneChip.Mouse430A_2 chips single channel were used.

ORGANISM(S): Mus musculus  

SUBMITTER: Sergiy Libert  Leonard Guarente    

PROVIDER: E-GEOD-28790 | ArrayExpress | 2011-05-18

SECONDARY ACCESSION(S): GSE28790PRJNA138829

REPOSITORIES: GEO, ArrayExpress

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