Transcriptomics

Dataset Information

18

EMT is the dominant program in human colon cancer


ABSTRACT: This SuperSeries is composed of the following subset Series: GSE28567: EMT is the dominant program in human colon cancer (Affymetrix) GSE28709: EMT is the dominant program in human colon cancer (lung) GSE28722: EMT is the dominant program in human colon cancer (Agilent) Refer to individual Series

ORGANISM(S): Homo sapiens  

SUBMITTER: Michael Nebozhyn  

PROVIDER: E-GEOD-28814 | ArrayExpress | 2011-04-25

SECONDARY ACCESSION(S): GSE28814PRJNA138767

REPOSITORIES: GEO, ArrayExpress

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Publications


Colon cancer has been classically described by clinicopathologic features that permit the prediction of outcome only after surgical resection and staging.We performed an unsupervised analysis of microarray data from 326 colon cancers to identify the first principal component (PC1) of the most variable set of genes. PC1 deciphered two primary, intrinsic molecular subtypes of colon cancer that predicted disease progression and recurrence.Here we report that the most dominant pattern of intrinsic g  ...[more]

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