Transcriptomics

Dataset Information

63

Global transcriptome analysis of mouse uterus during embryo implantation by SAGE


ABSTRACT: The aim of this study was to examine differential gene expression profile in mouse uterus on day 5 of pregnancy between implantation sites and inter-implantation sites. There are 104,520 tags sequenced and acquired, 51,306 for non-implantation site, and 53,214 for implantation site. Keywords: Implantation, Uterus, Differential gene expression, Implantation sites and inter-implantation sites were isolated from the mouse uteri on day 5 of pregnancy from at least 20 mice. Implantation sites were identified by tail-vein injection of 0.1 ml of 1% Chicago blue 5 min before sample collection. SAGE analysis was used to examine differential gene expression in mouse uterus during embryo implantation.

ORGANISM(S): Mus musculus  

SUBMITTER: Ji L Liu   Yue C Zhao  Xing H Ma  Zhen Tian  Zeng-Ming Yang  Ping Wan  Zeng M Yang  Hua Ni  Shi J Hu 

PROVIDER: E-GEOD-2892 | ArrayExpress | 2005-07-13

SECONDARY ACCESSION(S): GSE2892PRJNA92589

REPOSITORIES: GEO, ArrayExpress

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Publications

Serial analysis of gene expression in mouse uterus at the implantation site.

Ma Xing-Hong XH   Hu Shi-Jun SJ   Ni Hua H   Zhao Yue-Chao YC   Tian Zhen Z   Liu Ji-Long JL   Ren Gang G   Liang Xiao-Huan XH   Yu Hao H   Wan Ping P   Yang Zeng-Ming ZM  

The Journal of biological chemistry 20060124 14


Although oligonucleotide chips, cDNA microarrays, differential display reverse transcription-PCR, and other approaches have been used to screen implantation-related molecules, the mechanism by which embryo implantation occurs is still unknown. The aim of this study was to profile the differential gene expression between interimplantation site and implantation site in mouse uterus on day 5 of pregnancy by serial analysis of gene expression (SAGE). In our two SAGE libraries of 11-bp tags, the tota  ...[more]

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