Dataset Information


Analysis of p53 target genes in melanoma part 1

ABSTRACT: Although mutations in p53 are infrequent in human melanoma, its function is abnormal. In this study, whole genome bead arrays were used to examine the expression of p53 target genes in extracts from 82 metastatic melanoma samples, compared to extracts derived from diploid human melanocytes, to provide a global assessment of aberrant p53 function. Total RNA extracted from 82 tumour samples and 8 melanocyte cell lines was analysed. Metastatic melanomas were compared to melanocyte cell lines.

ORGANISM(S): Homo sapiens  

SUBMITTER: Helen Rizos   Lyndee L Scurr  Rodney J Scott  Peter Hersey  Katie A Ashton  Carla Kairupan  Kelly Kiejda  Bente A Talseth-Palmer  Amanda J Croft  Xu D Zhang  Kelly A Avery-Kiejda  Nikola A Bowden 

PROVIDER: E-GEOD-29359 | ArrayExpress | 2011-12-01



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